Pearl of Wisdom: Shaping Genomic Therapies & Community Research with Dr. Jocelynn Pearl.
Jocelynn Pearl, a life scientist, podcast host, and advocate for decentralized science, joins Karl and Erum to discuss the future of biotech and the exciting developments happening in the field. Jocelynn shares her experiences in gene editing, specifically with zinc fingers and TALENs, and how the advent of CRISPR has revolutionized the field. She also highlights the significance of epigenome editing and its potential for treating diseases. Jocelynn discusses the concept of decentralized science and its impact on scientific publishing and collaboration. They conclude with a discussion on the future of biotech, where advancements in therapeutics are expected to lead to significant improvements in patient care.
Topics Covered
00:00:00 Discussing Climate Change and Lab-grown Food: Possible Relief for Global Farmers
00:01:24 Unpacking the Benefits and Common Concerns About Lab-grown Food
00:03:56 Addressing Antibiotics in Livestock and the Impact on Grocery Prices
00:05:10 Exploring the Disparity in Subsidies: The Overemphasis on Fossil Fuel and Highways Over Trains
00:07:26 The Promise of Maglev Trains and Quantum Computing: A Peek Into the Future
00:11:35 Bridging Biology and Technology: An Insight into Biotech Consulting
00:14:32 Speculations on Extraterrestrial Contact: Is It Around the Corner?
00:16:19 Women in Leadership: Reflecting on a Three-Year Journey of Empowering Narratives
00:19:48 The Advent of CRISPR: A Landmark in DNA Editing Revolution Since 2010
00:21:50 Unraveling the Role of Epigenome Editing in Disease Therapeutics
00:23:36 The Epigenetic Approach: Modulating Gene Expression Without DNA Cleavage
00:25:24 Enhancing Human Performance: The Untapped Potential of the Epigenome
00:27:14 The Metformin Study: A Crowdfunded Initiative to Understand Population-wide Effects
00:31:10 The Dawn of Decentralized Science: Envisioning the Future Beyond Regulatory Boundaries
00:33:28 Blockchain Meets Science: A Potential Upheaval in Scientific Publishing
00:37:34 Enhancing Drug Development with Advanced Computational Tools and Protein Structure Prediction
00:39:58 The Biotech Horizon: Predictions and Insights from an Industry Expert
00:42:05 The Rise of Targeted Therapeutics: A New Era in Drug Discovery
00:44:54 A Journey Through Time: Memorable Milestones in Challenging Scientific Careers
00:48:03 Jocelynn's Horticultural Hobby: A Deep Dive into House Plants and Avocado Trees
00:50:23 Seattle's Growing Oasis: Figs, Lavender, Vegetables, and Family Bonds
00:54:03 The 'Grow Everything' Hotline and the Passion for Green Living
Topics Covered
Jocelynn Pearl on LinkedIn
World Farmers’ Organization - Anti Lab-grown food statement
Venture City on Youtube - Mars timelapse
Astera Institute - Unblocking Scientific Publishing
Golden Age of Medicine - New York Times
“For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug” by Nathan Vardi.
Chasing My Cure by David Fajgenbaum